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Imma Ratera's lab. Biomaterials and molecular electronics


rateraDra. Imma Ratera


perezDr. Eduardo Pérez 


MarcMarc Martínez
Nerea fotoNerea González
xavi2Xavier Rodríguez 

Fabiao SantosFabiao santos 



Roberto Matinez SolerRoberto Martínez Soler

Former Students:

PhD students:

  • Adriana Kyvik

 Master students:

  • Jara arcas
  • Emilia Schneider
  • Julia Valderas
  • Hanna Reijneveld


Imma Ratera's Publications


  • Methods for the Characterization of Protein Aggregates. Marc Martínez-Miguel, Witold Tatkiewicz, Mariana Köber, Nora Ventosa, Jaume Veciana, Judith Guasch, Imma Ratera.
    Methods Mol Biol. DOI:10.1007/978-1-0716-1859-2_29.
  • Methods for Processing Protein Aggregates into Surfaces. Marc Martínez-Miguel, Witold Tatkiewicz, Mariana Köber, Nora Ventosa, Jaume Veciana, Judith Guasch, Imma Ratera.
    Methods Mol Biol. DOI:10.1007/978-1-0716-1859-2_31.
  • o-Carborane-based fluorophores as efficient luminescent systems both as solids and as water-dispersible nanoparticles. Sohini Sinha, Zsolt Kelemen, Evelyn Hümpfner, Imma Ratera, Jean-Pierre Malval, José Piers Jurado, Clara Viñas, Francesc Teixidor, Rosario Núñez.
    Chem Commun (Camb). DOI:10.1039/d1cc07211k.


  • Polylactide, Processed by a Foaming Method Using Compressed Freon R134a, for Tissue Engineering. María Aguado, Laura Saldaña, Eduardo Pérez Del Río, Judith Guasch, Marc Parera, Alba Córdoba, Joaquín Seras-Franzoso, Olivia Cano-Garrido, Esther Vázquez, Antonio Villaverde, Jaume Veciana, Imma Ratera, Nuria Vilaboa, Nora Ventosa.
    Polymers (Basel). DOI:10.3390/polym13203453.


  • CCL21-loaded 3D hydrogels for T cell expansion and differentiation. Eduardo Pérez Del Río, Fabião Santos, Xavier Rodriguez Rodriguez, Marc Martínez-Miguel, Ramon Roca-Pinilla, Anna Arís, Elena Garcia-Fruitós, Jaume Veciana, Joachim P Spatz, Imma Ratera, Judith Guasch .
    Biomaterials. DOI:10.1016/j.biomaterials.2020.120313.
  • An Enantiopure Propeller-Like Trityl-Brominated Radical: Bringing Together a High Racemization Barrier and an Efficient Circularly Polarized Luminescent Magnetic Emitter. Paula Mayorga-Burrezo, Vicente G Jiménez, Davide Blasi, Teodor Parella, Imma Ratera, Araceli G Campaña, Jaume Veciana.
    Chemistry.. DOI:10.1002/chem.202000098.


  • Effect of the Molecular Polarizability of SAMs on the Work Function Modification of Gold: Closed- versus Open-Shell Donor–Acceptor SAMs. Advanced Materials Technologies, (2019) 4, 5, 1800152. Diez-Cabanes, V., Morales, D.C., Souto, M., Paradinas, M., Delchiaro, F., Painelli, A., Ocal, C., Cornil, D., Cornil, J., Veciana, J., Ratera, I.
  • Two-dimensional self-assembly and electrical properties of the donor-acceptor tetrathiafulvalene-polychlorotriphenylmethyl radical on graphite substrates. Journal of Applied Physics, (2019) 125, 14, 142909. Guasch, J., Crivillers, N., Souto, M., Ratera, I., Rovira, C., Samorì, P., Veciana, J.
  • Cell Type-Dependent Integrin Distribution in Adhesion and Migration Responses on Protein-Coated Microgrooved Substrates. ACS Omega, (2019) 4, 1, 1791-1800. Sales, A., Ende, K., Diemer, J., Kyvik, A.R., Veciana, J., Ratera, I., Kemkemer, R., Spatz, J., Guasch, J.
  • Reversible switching of the Au(111) work function by near infrared irradiation with a bistable SAM based on a radical donor-acceptor dyad. Journal of Materials Chemistry C, (2019) 7, 24, 7418-7426. Diez-Cabanes, V., Gómez, A., Souto, M., González-Pato, N., Cornil, J., Veciana, J., Ratera, I.
  • High-Throughput Cell Motility Studies on Surface-Bound Protein Nanoparticles with Diverse Structural and Compositional Characteristics. ACS Biomaterials Science and Engineering, (2019) 5, 10, 5470-5480. Witold I. Tatkiewicz, Joaquin Seras-Franzoso, Elena García-Fruitós, Esther Vazquez, Adriana R. Kyvik, Nora Ventosa, Judith Guasch, Antonio Villaverde, Jaume Veciana, and Imma Ratera.
  • Functionalization of polyacrylamide for nanotrapping positively charged biomolecules. RSC Advances, (2019) 9, 27, 15402-15409. Davydova, N., Rodriguez, X.R., Blázquez, C., Gómez, A., Perevyazko, I., Guasch, J., Sergeev, V., Laukhina, E., Ratera, I., Veciana, J.


  • Insights into the structure and nanomechanics of a quatsome membrane by force spectroscopy measurements and molecular simulations. NanoscaleVol:10, Issue 48, 2018, 23001-23011. Gumí-Audenis, B., Illa-Tuset, S., Grimaldi, N., Pasquina-Lemonche, L., Ferrer-Tasies, L., Sanz, F., Veciana, J., Ratera, I., Faraudo, J., Ventosa, N., Giannotti, M.I.
  • Artificial 3D Culture Systems for T Cell Expansion.
    ACS Omega, 2018, 3 (5), pp 5273–5280.
    Eduardo Pérez del Río, Marc Martínez Miguel, Jaume Veciana, Imma Ratera,* and Judith Guasch*.
  • Stimuli-Responsive Functionalization Strategies to Spatially and Temporally Control Surface Properties: Michael vs Diels-Alder Type Additions.
    The journal of physical chemistry B, Vol: 122 Num: 16 Pag: 4481-4490
    Kyvik, Adriana R; Luque-Corredera, Carlos; Pulido, Daniel; Royo, Miriam; Veciana, Jaume; Guasch, Judith; Ratera, Imma
  • Role of the Open-Shell Character on the Pressure-Induced Conductivity of an Organic Donor-Acceptor Radical Dyad.
    CHEMISTRY-A EUROPEAN JOURNAL Vol: 24, Num: 21, Pag: 5500-5505; Souto, M; Gullo, MC; Cui, HB; Casati, N; Montisci, F; Jeschke, HO; Valenti, R; Ratera, I; Rovira, C; Veciana, J
  • Highly Stable and Red‐Emitting Nanovesicles Incorporating Lipophilic Diketopyrrolopyrroles for Cell Imaging.
    Chem. Eur. J. 2018, 24, 1 – 8. 
    A. Ardizzone, D. Blasi, D. Vona, A. Rosspeintner, A. Punzi, E. Altamura, N. Grimaldi, S. Sala, E. Vauthey, G. M. Farinola, I. Ratera, N. Ventosa, J. Veciana.
  • Surface-Bound Gradient Deposition of Protein Nanoparticles for Cell Motility Studies.
    ACS Appl. Mater. Interfaces, 2018, 10 (30), pp 25779–25786.
    W. I. Tatkiewicz, J. Seras-Franzoso, E. Garcia-Fruitós, E. Vazquez, A.R. Kyvik, J. Guasch, A. Villaverde, J. Veciana, and I. Ratera.
  • Pulling lipid tubes from supported bilayers unveils the underlying substrate contribution to the membrane mechanics.
    Nanoscale, 2018, 10, 14763.
    B. Gumí-Audenis, L. Costa, L. Ferrer-Tasies, I. Ratera, N. Ventosa, F. Sanza, and M. I. Giannotti.


  • Integrin-Assisted T-Cell Activation on Nanostructured Hydrogels.
    Nano Letters, Volume 17, Issue 10, oct - 2017, Pages 6110 – 6116.
    Guasch J., Muth C.A., Diemer J., Riahinezhad H., Spatz J.P.
  • Tetrathiafulvalene-Polychlorotriphenylmethyl Dyads: Influence of Bridge and Open-Shell Characteristics on Linear and Nonlinear Optical Properties.
    CHEMISTRY-A EUROPEAN JOURNAL Vol 23, Num 46, Pag 11067-11075. Souto, M; Calbo, JN; Ratera, I; Orti, E; Veciana, J
  • Conflicting evidence for ferroelectricity.
    NATURE Vol: 547 Num: 7662 Pag: E9-E13.
    D'Avino, G; Souto, M; Masino, M; Fischer, JKH; Ratera, I; Fontrodona, X; Giovannetti, G; Verstraete, MJ; Painelli, A; Lunkenheimer, P; Veciana, J; Girlando, A
  • TTF–PTM dyads: from switched molecular self assembly in solution to radical conductors in solid state.
    CrystEngComm, 2017, 19, 197-206.
    M. Souto, C. Rovira, I. Ratera and J. Veciana
  • Tuning the Rectification Ratio by Changing the Electronic Nature (Open-Shell and Closed-Shell) in Donor−Acceptor Self-Assembled Monolayers.
    J. Am. Chem. Soc. 2017, 139, 4262−4265.
    M. Souto, L. Yuan, D. C. Morales, L. Jiang, I. Ratera, C. A. Nijhuis, and J. Veciana
  • Excimers from stable and persistent supramolecular radical-pairs in red/NIR-emitting organic nanoparticles and polymeric films.
    Phys. Chem. Chem. Phys., 2017, 19, 9313.
    D. Blasi, D. M. Nikolaidou, F. Terenziani, I. Ratera and J. Veciana


  • Functional protein-based nanomaterial produced in microorganisms recognized as safe: A new platform for biotechnology.
    Acta Biomaterialia 43 (2016) 230–239.
    O. Cano-Garrido, A. Sánchez-Chardi, S. Parés, I. Giró, W. I. Tatkiewicz, N. Ferrer-Miralles, I. Ratera, A. Natalello, R. Cubarsi, J. Veciana, À. Bach, A. Villaverde, A. Arís, E. Garcia-Fruitós.
  • DT-TTF Salts with [Cu(dcdmp)2] −: The Richness of Different Stoichiometries.
    Cryst. Growth Des. 2016, 16, 3924−3931.
    R. A. L. Silva, I. C. Santos, E. B. Lopes, S. Rabaca, J. Vidal-Gancedo, C. Rovira, M. Almeida, D. Belo.
  • 1,2,3-Triazole–Diketopyrrolopyrrole Derivatives with TunableSolubility and Intermolecular Interactions.
    Eur. J. Org. Chem. 2016, 2617–2627
    A. Punzi, E. Maiorano, F. Nicoletta, D. Blasi, A. Ardizzone, N. Ventosa, I. Ratera, J. Veciana and G. M. Farinola.
  • Three Redox States of a Diradical Acceptor-Donor-Acceptor Triad: Gating the Magnetic Coupling and the Electron Delocalization.
    Journal of physical chemistry letters, 2016, Vol. 7 Número 12 Páginas 2234-2239.
    Souto, M; Lloveras, V, Vela, S, Fumanal, M, Ratera, I, Veciana, J.
  • Understanding the Influence of the Electronic Structure on the Crystal Structure of a TTF-PTM Radical Dyad.
    J. Phys. Chem. A 2016, 120, 10297−10303.
    S. Vela, M. Souto, I. Ratera, C. Rovira, and J. Veciana
  • Pressure-Induced Conductivity in a Neutral Nonplanar SpinLocalized Radical.
    J. Am. Chem. Soc. 2016, 138, 11517−11525.
    M. Souto, H.B. Cui, M. Peña-Álvarez, V. G. Baonza, H. O. Jeschke, M. Tomic, R. Valentí, D. Blasi, I. Ratera, C. Rovira, and J. Veciana
  • Synthesis and Characterization of Ethylenedithio-MPTTF-PTM Radical Dyad as a Potential Neutral Radical Conductor.
    Magnetochemistry 2016, 2, 46.
    M. Souto, D. Bendixen, M. Jensen, V. Díez-Cabanes, J. Cornil, J. O. Jeppesen, I. Ratera, C. Rovira and J. Veciana
  • 1,2,3-Triazole–Diketopyrrolopyrrole Derivatives with Tunable Solubility and Intermolecular Interactions.
    EurJoc, Volume 2016, Issue 15, May 2016, Pages 2617–2627
    Angela Punzi, Eliana Maiorano, Francesca Nicoletta, Davide Blasi, Antonio Ardizzone, Nora Ventosa, Imma Ratera, Jaume Veciana* and Gianluca Maria Farinola.


  • Self-Assembled Architectures with Segregated Donor and Acceptor Units of a Dyad Based on a Monopyrrolo-Annulated TTF-PTM Radical.
    Chemistry-a european journal, 2015, 21 (24), 8816-8825.
    M. Souto, M. V. Solano, M. Jensen, D. Bendixen, F. Delchiaro, A. Girlando, A. Painelli, J. O. Jeppesen, C. Rovira, I. Ratera, J. Veciana
  • Organic radicals for the enhancement of oxygen reduction reaction in Li-O2 batteries.
    Chemical communications 2015, 51 - 99, pp. 17623 -6.
    Tesio, A Y; Blasi, D; Olivares-Marin, M; Ratera, I; Tonti, D; Veciana, J.
  • Integrating mechanical and biological control of cell proliferation through bioinspired multieffector materials.
    Nanomedicine 2015, 10(5), pp 873–891.
    J. Seras-Franzoso, W. I Tatkiewicz, E. Vazquez, E. García-Fruitós, I. Ratera, J. Veciana, A. Villaverde


  • Methods for characterization of protein aggregates.
    Methods in molecular biology (Clifton, N.J.) 2015, 1258, 387-401.
    W. Tatkiewicz, E. Elizondo, E. Moreno, C. Diez-Gil, N. Ventosa, J. Veciana, I. Ratera.


  • In Vivo Architectonic Stability of Fully de Novo Designed Protein-Only Nanoparticles.
    ACS NANO 2014, 8 (5) 4166-4176.
    M V. Cespedes, U. Unzueta, W. Tatkiewicz, A. Sanchez-Chardi, O. Conchillo-Sole, P. Alamo, Z. Xu, I. Casanova, J. L. Corchero, M. Pesarrodona, J. Cedano, X. Daura, I. Ratera, J. Veciana, N. Ferrer-Miralles, E. Vazquez, A. Villaverde, and R. Mangues.
  • Highly sensitive and selective detection of the pyrophosphate anion biomarker under physiological conditions.
    Chem. Sci., 2014, 5, 2328.
    G. Sánchez, D. Curiel, W. Tatkiewcz, I. Ratera, A. Tárraga, J. Veciana and P. Molina.
  • Intracellular targeting of CD44+ cells with self-assembling, protein only nanoparticles.
    International Journal of Pharmaceutics 2014, 473, 286–295.
    M. Pesarrodona, N. Ferrer-Miralles, U. Unzueta, P. Gener, W. Tatkiewicz, I. Abasolo, I. Ratera, J. Veciana, S. Schwartz Jr, A. Villaverde, E. Vazquez.
  • Intramolecular electron transfer and charge delocalization in bistable donor–acceptor systems based on perchlorotriphenylmethyl radicals linked to ferrocene and tetrathiafulvalene units.
    J. Phys. Org. Chem. 2014, 27, 465–469.
    M. Souto, D. C. Morales, J. Guasch, I. Ratera, C. Rovira, A. Painelli and J. Veciana.


  • Engineering Protein Based Nanoparticles for Applications in Tissue Engineering.
    Bio- and Bioinspired Nanomaterials pp. 425-447. Wiley. Edited by D. Ruiz-Molina, F. Novio and C. Roscini.2014. ISBN: 978-3-527-33581-7.
    W.I. Tatkiewicz, Joaquin Seras-Franzoso, C. Díez-Gil, E. García Fruitós, E. Vázquez, I. Ratera, A. Villaverde, and Jaume Veciana.


  • Two-dimensional microscale engineering of protein-based nanoparticles for cell guidance.
    ACS nano 2013, 7, 6, 4774-84.
    W. I. Tatkiewicz, J. Seras-Franzoso, E. Garcia-Fruitos, E. Vazquez, N. Ventosa, K. Peebo, I. Ratera, A. Villaverde, J. Veciana.
  • Supramolecular organization of protein-releasing functional amyloids solved in bacterial inclusion bodies.
    Acta Biomaterialia 2013, 9, 6134–6142.
    O. Cano-Garrido, E. Rodriguez-Carmona, C. Diez-Gil, E. Vazquez, E. Elizondo, R. Cubarsi, J. Seras-Franzoso, J.L. Corchero, U. Rinas, I. Ratera, N. Ventosa, J. Veciana, A. Villaverde, E. Garcia-Fruitos.
  • The perchlorotriphenylmethyl (PTM) radical.
    Acta Cryst. 2013, C69, 255–257.
    J. Guasch, X. Fontrodona, I. Ratera, C. Rovira, J. Veciana.
  • PDMS based photonic lab-on-a-chip for the selective optical detection of heavy metal ions.
    Analyst 2013, 138, 839.
    B. Ibarlucea, C. Díez-Gil, I. Ratera, J. Veciana, A. Caballero, F. Zapata, A. Tárraga, P. Molina, S. Demming, S. Büttgenbach, C. Fernández-Sánchez, A. Llobera.
  • Bistability of Fc-PTM-Based Dyads: The Role of the Donor Strength.
    Chem. Mater. 2013, 25, 808−814.
    J. Guasch, L. Grisanti, S. Jung, D. Morales, G. D'Avino, M. Souto, X. Fontrodona, A. Painelli, F. Renz, I. Ratera, J. Veciana.
  • Modified mesoporous silica nanoparticles as a reusable, selective chromogenic sensor for mercury(II) recognition.
    Dalton Trans. 2013, 42, 6318.
    G. Sánchez, D. Curiel, I. Ratera, A. Tárraga, J. Veciana, P. Molina.
  • Intra- and Intermolecular Charge Transfer in Aggregates of Tetrathiafulvalene-Triphenylmethyl Radical Derivatives in Solution.
    J. Am. Chem. Soc. 2013, 135, 6958−6967.
    J. Guasch, L. Grisanti, M. Souto, V. Lloveras, J. Vidal-Gancedo, I. Ratera, A. Painelli, C. Rovira, J. Veciana.
  • Thermomagnetic Molecular System Based on TTF-PTM Radical: Switching the Spin and Charge Delocalization.
    J. Phys. Chem. Lett. 2013, 4, 2721−2726.
    M. Souto, J. Guasch, V. Lloveras, P. Mayorga, J. T. López Navarrete, J. Casado, I. Ratera, C. Rovira, A. Painelli, J. Veciana.
  • Functionalization of 3D scaffolds with protein-releasing biomaterials for intracellular delivery.
    Journal of Controlled Release 2013, 171, 63–72.
    J. Seras-Franzoso, C. Steurer, M. Roldán, M. Vendrell, C. Vidaurre-Agut, A. Tarruella, L. Saldaña, N. Vilaboa, M. Parera, E. Elizondo, I. Ratera, N. Ventosa, J. Veciana, A. J. Campillo-Fernández, E. García-Fruitós, E. Vázquez, A. Villaverde.


  • Sensing Hg(II) ions in water: From molecules to nanostructured molecular materials.
    Organic Nanomaterials: Synthesis, Characterization, and Device Applications; Eds. Torres, Tomás; Bottari, Giovanni. Chapter 24. John Wiley & Sons, Inc. (2013)
    Imma Ratera, Alberto Tárraga, Pedro Molina and Jaume Veciana.


  • Supramolecular organization of protein-releasing functional amyloids solved in bacterial inclusion bodies.
    Acta Biomater. 2012, S1742-7061(12)00583-1.
    Cano-Garrido O, Rodríguez-Carmona E, Díez-Gil C, Vázquez E, Elizondo E, Cubarsi R, Seras-Franzoso J, Corchero JL, Rinas U, Ratera I, Ventosa N, Veciana J, Villaverde A, García-Fruitós E.
  • Induced Self-Assembly of a Tetrathiafulvalene-Based Open-ShellDyad through Intramolecular Electron Transfer.
    Angew. Chem. Int. Ed. 51, 2012, 124, 11186 –11190.
    J. Guasch, L. Grisanti, V. Lloveras, J. Vidal-Gancedo, M. Souto, D. C. Morales, M. Vilaseca, C. Sissa, A. Painelli, I. Ratera, C. Rovira, and J. Veciana.
  • Playing with organic radicals as building blocks for functional molecular materials.
    Chem. Soc. Rev., 41, 2012, 303–349.
    I. Ratera, J. Veciana.
  • Bioadhesiveness and efficient mechanotransduction stimuli synergistically provided by bacterial inclusion bodies as scaffolds for tissue engineering.
    Nanomedicine 2012, 7 (1) 79-93.
    J. Seras-Franzoso, C. Díez-Gil, E. Vazquez, E. García-Fruitós, R. Cubars, I. Ratera, J. Veciana, A. Villaverde.
  • Bacterial inclusion bodies: making gold from waste.
    Trends in Biotechnology 2012, 30, 2, 65–70.
    E. García-Fruitós, E. Vázquez, C. Díez-Gil, J. L. Corchero, J. Seras-Franzoso, I. Ratera, J. Veciana, A. Villaverde.