Nora Ventosa's Lab. Nanomedicine

PERMANENT STAFF

ventosaDra. Nora Ventosa

POST-DOCTORAL RESEARCHERS

Gonzalez Dra. Elisabet González
kober Dra. Mariana Kober
Judit morla foto 02Judit Morlà

 tomsenDra. Judit Tomsen

PhD STUDENTS

Aida Carreño
Marc Martínez
 Rubén García Costas
 Carla Castellar Alvarez
 Marta Alcaina Hernando
 Nerea González Pato
 

TECHNICAL STAFF

Amable Bernabé
David Piña
Arnau Jaumandreau
 



 
 

Nora Ventosa's Publications

2022

  • Methods for the Characterization of Protein Aggregates. Marc Martínez-Miguel, Witold Tatkiewicz, Mariana Köber, Nora Ventosa, Jaume Veciana, Judith Guasch, Imma Ratera. Methods Mol Biol. DOI:10.1007/978-1-0716-1859-2_29.
  • Methods for Processing Protein Aggregates into Surfaces. Marc Martínez-Miguel, Witold Tatkiewicz, Mariana Köber, Nora Ventosa, Jaume Veciana, Judith Guasch, Imma Ratera. Methods Mol Biol. DOI:10.1007/978-1-0716-1859-2_31.
  • DELOS Nanovesicles-Based Hydrogels: An Advanced Formulation for Topical Use. Lídia Ballell-Hosa, Elisabet González-Mira, Hector Santana, Judit Morla-Folch, Marc Moreno-Masip, Yaima Martínez-Prieto, Albert Revuelta, Primiano Pio Di Mauro, Jaume Veciana, Santi Sala, Lidia Ferrer-Tasies, Nora Ventosa. Pharmaceutics. DOI:10.3390/pharmaceutics14010199

2021

  •  Polylactide, Processed by a Foaming Method Using Compressed Freon R134a, for Tissue Engineering. María Aguado, Laura Saldaña, Eduardo Pérez Del Río, Judith Guasch, Marc Parera, Alba Córdoba, Joaquín Seras-Franzoso, Olivia Cano-Garrido, Esther Vázquez, Antonio Villaverde, Jaume Veciana, Imma Ratera, Nuria Vilaboa, Nora Ventosa. Polymers (Basel). DOI:10.3390/polym13203453.
  • Application of Quality by Design to the robust preparation of a liposomal GLA formulation by DELOS-susp method. Josep Merlo-Mas, Judit Tomsen-Melero, José-Luis Corchero, Elisabet González-Mira, Albert Font, Jannik N Pedersen, Natalia García-Aranda, Edgar Cristóbal-Lecina, Marta Alcaina-Hernando, Rosa Mendoza, Elena Garcia-Fruitós, Teresa Lizarraga, Susanne Resch, Christa Schimpel, Andreas Falk, Daniel Pulido, Miriam Royo, Simó Schwartz Jr, Ibane Abasolo, Jan Skov Pedersen, Dganit Danino, Andreu Soldevila, Jaume Veciana, Santi Sala, Nora Ventosa, Alba Córdoba. J Supercrit Fluids. DOI:10.1016/j.supflu.2021.105204.
  • Impact of Chemical Composition on the Nanostructure and Biological Activity of α-Galactosidase-Loaded Nanovesicles for Fabry Disease Treatment. Judit Tomsen-Melero, Solène Passemard, Natalia García-Aranda, Zamira Vanessa Díaz-Riascos, Ramon González-Rioja, Jannik Nedergaard Pedersen, Jeppe Lyngsø, Josep Merlo-Mas, Edgar Cristóbal-Lecina, José Luis Corchero, Daniel Pulido, Patricia Cámara-Sánchez, Irina Portnaya, Inbal Ionita, Simó Schwartz Jr, Jaume Veciana, Santi Sala, Miriam Royo, Alba Córdoba, Dganit Danino, Jan Skov Pedersen, Elisabet González-Mira, Ibane Abasolo, Nora Ventosa. ACS Appl Mater Interfaces. DOI:10.1021/acsami.0c16871.
  • Engineering pH-Sensitive Stable Nanovesicles for Delivery of MicroRNA Therapeutics. Ariadna Boloix, Natalia Feiner-Gracia, Mariana Köber, Javier Repetto, Rosa Pascarella, Aroa Soriano, Marc Masanas, Nathaly Segovia, Guillem Vargas-Nadal, Josep Merlo-Mas, Dganit Danino, Inbal Abutbul-Ionita, Laia Foradada, Josep Roma, Alba Córdoba, Santi Sala, Josep Sánchez de Toledo, Soledad Gallego, Jaume Veciana, Lorenzo Albertazzi, Miguel F Segura, Nora Ventosa. Small. DOI:10.1002/smll.202101959.

2020

  • Use of N-oxide and cationic surfactants to enhance antioxidant properties of (+)-usnic acid loaded liposomes. Sara Battista, Patrizio Campitelli, L. Galantini, M. Köber, Guillem Vargas-Nadal, N. Ventosa. Colloids and Surfaces A: Physicochemical and Engineering Aspects. DOI:10.1016/j.colsurfa.2019.124154. 
  • MKC-Quatsomes: a stable nanovesicle platform for bio-imaging and drug-delivery applications. Guillem Vargas-Nadal, Mónica Muñoz-Úbeda, Patricia Álamo, Montserrat Mitjans, Virtudes Céspedes, Mariana Köber, Elisabet González-Mira, Lidia Ferrer-Tasies, Maria Pilar Vinardell, Ramón Mangues, Jaume Veciana, Nora Ventosa. Nanomedicine: Nanotechnology, Biology, and Medicine. DOI:10.1016/j.nano.2019.102136. 
  • Dye-Loaded Quatsomes Exhibiting FRET as Nanoprobes for Bioimaging. Morla Folch, Judit; Vargas Nadal, Guillem; Zhao, Tinghan; Sissa, Cristina; Ardizzone, Antonio CSIC ORCID; Kurhuzenkau, Siarhei; Köber, Mariana; Uddin, Mehrun; Painelli, Anna; Veciana, Jaume; Belfield, Kevin D.; Ventosa, Nora ACS applied materials & interfaces. DOI:10.1021/acsami.0c03040. 
  • Stable anchoring of bacteria-based protein nanoparticles for surface enhanced cell guidance. Marc Martínez-Miguel, Adriana R. Kyvik, Lena M. Ernst, Albert Martínez-Moreno, Olivia Cano-Garrido, Elena Garcia-Fruitós, Esther Vazquez, Nora Ventosa, Judith Guasch, Jaume Veciana, Antonio Villaverde and  Imma Ratera. Journal of Materials Chemistry B. DOI:10.1039/d0tb00702a. 
  • Stable anchoring of bacteria-based protein nanoparticles for surface enhanced cell guidance. Marc Martínez-Miguel, Adriana R. Kyvik, Lena M. Ernst, Albert Martínez-Moreno, Olivia Cano-Garrido, Elena Garcia-Fruitós, Esther Vazquez, Nora Ventosa, Judith Guasch, Jaume Veciana, Antonio Villaverde and  Imma Ratera. Journal of Materials Chemistry B. DOI:10.1039/d0tb00702a

2019

  • A fast and remote screening method for sub-micro-structuration in pressurized mixtures containing water and carbon dioxide. Stehle, Simon; Lay, Ebrahim Nemati; Triolo, Alessandro; Ventosa, Nora; Braeuer, Andreas Siegfried Journal of Supercritical Fluids. DOI:10.1016/j.supflu.2019.104555. 
  • High-Throughput Cell Motility Studies on Surface-Bound Protein Nanoparticles with Diverse Structural and Compositional Characteristics. Witold I. Tatkiewicz, Joaquin Seras-Franzoso, Elena García-Fruitós, Esther Vazquez, Adriana R. Kyvik, Nora Ventosa, Judith Guasch, Antonio Villaverde, Jaume Veciana, and Imma Ratera ACS Biomaterials Science and Engineerings. DOI:10.1021/acsbiomaterials.9b01085.

2018

  • Impact Of Physicochemical Properties Of DNA/PEI Complexes On Transient Transfection Of Mammalian Cells. Gonzalez-Dominguez, I; Grimaldi, N; Cervera, L; Ventosa, N; Godia, F New Biotechnology, 49, 88-97. DOI:10.1016/J.Nbt.2018.09.005. 
  • Insights Into The Structure And Nanomechanics Of A Quatsome Membrane By Force Spectroscopy Measurements And Molecular Simulations Gumi-Audenis, B; Illa-Tuset, S; Grimaldi, N; Pasquina-Lemonche, L; Ferrer-Tasies, L; Sanz, F; Veciana, J; Ratera, I; Faraudo, J; Ventosa, N.; Giannotti, MI Nanoscale, 10, 48, 23001-23011. DOI: 10.1039/C8nr07110a
  • Pulling lipid tubes from supported bilayers unveils the underlying substrate contribution to the membrane mechanics.
    Nanoscale, 2018, 10, 14763.
    B. Gumí-Audenis, L. Costa, L. Ferrer-Tasies, I. Ratera, N. Ventosa, F. Sanza, and M. I. Giannotti.
  • Highly Stable and Red‐Emitting Nanovesicles Incorporating Lipophilic Diketopyrrolopyrroles for Cell Imaging.
    Chem. Eur. J. 2018, 24, 1 – 8. 
    A. Ardizzone, D. Blasi, D. Vona, A. Rosspeintner, A. Punzi, E. Altamura, N. Grimaldi, S. Sala, E. Vauthey, G. M. Farinola, I. Ratera, N. Ventosa, J. Veciana.
  • Nanostructuring Lipophilic Dyes in Water Using Stable Vesicles, Quatsomes, as Scaffolds and Their Use as Probes for Bioimaging.
    SMALL, 14, 16, 1703851, 2018.
    Ardizzone, A; Kurhuzenkau, S; Illa-Tuset, S; Faraudo, J; Bondar, M; Hagan, D; Van Stryland, EW; Painelli, A; Sissa, C; Feiner, N; Albertazzi, L; Veciana, J.; Ventosa, N.

2017

  • Fluorenyl-Loaded Quatsome Nanostructured Fluorescent Probes
    Acs Omega  2,   8,  4112-4122
    Liu, XL; Ardizzone, A; Sui, BL; Anzola, M; Ventosa, N; Liu, TH; Veciana, J; Belfield, KD

  • Benznidazole Nanoformulates: A Chance to Improve Therapeutics for Chagas Disease.
    The American journal of tropical medicine and hygiene DOI:10.4269/ajtmh.17-0044
    Vinuesa, Teresa; Herraez, Rocio; Oliver, Laura; Elizondo, Elisa; Acarregui, Argia; Esquisabel, Amaia; Pedraz, Jose Luis; Ventosa, Nora; Veciana, Jaume; Vinas, Miguel

  • Pressure-Responsive, Surfactant-Free CO2-Based Nanostructured Fluids.
    ACS nano, Vol 11, Núm 11, Pág 10774-10784. 
    Grimaldi, N.; Rojas, P.E.; Stehle, S.; Cordoba, A.; Schweins, R.; Sala, S.; Luelsdorf, S.; Pina, D.; Veciana, J.; Faraudo, J.; Triolo, A.; Braeuer, A. S.; Ventosa, N.

  • Highly Fluorescent Silicon Nanocrystals Stabilized in Water Using Quatsomes
    LANGMUIR Volumen: 33, 50, 14366-14377. DEC 19 2017. DOI 10.1021/acs.langmuir.7b03539
    Silbaugh, DA; Ferrer-Tasies, L; Faraudo, J.; Veciana, J.; Ventosa, N.; Korgel, BA

2016

  • Lipid-based nanovesicles for nanomedicine.
    Chem. Soc. Rev., 2016, 45, 6520.
    N. Grimaldi, F. Andrade, N. Segovia, L. Ferrer-Tasies, S. Sala, J. Veciana and N. Ventosa.

  • 1,2,3-Triazole–Diketopyrrolopyrrole Derivatives with Tunable Solubility and Intermolecular Interactions.
    EurJoc, Volume 2016, Issue 15, May 2016, Pages 2617–2627
    Angela Punzi, Eliana Maiorano, Francesca Nicoletta, Davide Blasi, Antonio Ardizzone, Nora Ventosa, Imma Ratera, Jaume Veciana* and Gianluca Maria Farinola.

2015

  • Particle engineering with CO2-expanded solvents: the DELOS platform.
    Advances in Organic Crystal Chemistry: Comprehensive Reviews 2015, chapter 5, pp 73 - 94.
    Paula E. Rojas, Santi Sala, Elisa Elizondo, Jaume Veciana, Nora Ventosa.

  • Methods for characterization of protein aggregates.
    Methods in molecular biology (Clifton, N.J.) 2015, 1258, 387-401.
    W. Tatkiewicz, E. Elizondo, E. Moreno, C. Diez-Gil, N. Ventosa, J. Veciana, I. Ratera. Book Chapter.

2014

  • Surfactant-free CO2-based microemulsion-like systems.
    Chemical Communications 2014, 50 (60) 8215-8218.
    R. F. Hankel, P.E. Rojas, M. Cano-Sarabia, S. Sala, J. Veciana, A. Braeuer, N. Ventosa.

  • A New Microcrystalline Phytosterol Polymorph Generated Using CO2‑Expanded Solvents.
    Cryst. Growth Des. 2014, 14, 58−68.
    E. Moreno-Calvo, F. Temelli, A. Cordoba, N. Masciocchi, J. Veciana, N. Ventosa.

  • Methods for Characterization of Protein Aggregates.
    Insoluble Proteins. Methods and Protocols. pp. 387-402. Springer Protocols. Humana Press. 2015. ISBN 978-1-4939-2204-8.
    W. Tatkiewicz, E. Elizondo, Ev. Moreno, C. Díez-Gil, N. Ventosa, J. Veciana, and I. Ratera.

  • Surfactant-free CO2-based microemulsion-like systems.
    Chemical Communications 2014, 50 (60) 8215-8218.
    R. F. Hankel, P.E. Rojas, M. Cano-Sarabia, S. Sala, J. Veciana, A. Braeuer, N. Ventosa.

2013

  • Two-dimensional microscale engineering of protein-based nanoparticles for cell guidance.
    ACS nano 2013, 7, 6, 4774-84.
    W. I. Tatkiewicz, J. Seras-Franzoso, E. Garcia-Fruitos, E. Vazquez, N. Ventosa, K. Peebo, I. Ratera, A. Villaverde, J. Veciana.

  • Supramolecular organization of protein-releasing functional amyloids solved in bacterial inclusion bodies.
    Acta Biomaterialia 2013, 9, 6134–6142.
    O. Cano-Garrido, E. Rodriguez-Carmona, C. Diez-Gil, E. Vazquez, E. Elizondo, R. Cubarsi, J. Seras-Franzoso, J.L. Corchero, U. Rinas, I. Ratera, N. Ventosa, J. Veciana, A. Villaverde, E. Garcia-Fruitos.

  • Hydrophobic Gentamicin-Loaded Nanoparticles Are Effective against Brucella melitensis Infection in Mice.
    Antimicrobial agents and chemotherapy 2013, 57, 7, 3326-33.
    E. Imbuluzqueta, C. Gamazo, H. Lana, M.A. Campanero, D. Salas, A.G. Gil, E. Elizondo, N. Ventosa, J. Veciana, M.J. Blanco-Prieto.

  • Micro- and nanoformulation of APIs using CO2 expanded solvents.
    Chimica Oggi-Chemistry Today, 2013, 31, 6, 6-10.
    S. Sala, E. Elizondo, E. Moreno-Calvo, N. Ventosa, J. Veciana.

  • Functionalization of 3D scaffolds with protein-releasing biomaterials for intracellular delivery.
    Journal of Controlled Release 2013, 171, 63–72.
    J. Seras-Franzoso, C. Steurer, M. Roldán, M. Vendrell, C. Vidaurre-Agut, A. Tarruella, L. Saldaña, N. Vilaboa, M. Parera, E. Elizondo, I. Ratera, N. Ventosa, J. Veciana, A. J. Campillo-Fernández, E. García-Fruitós, E. Vázquez, A. Villaverde.

  • Quatsomes: Vesicles Formed by Self-Assembly of Sterols and Quaternary Ammonium Surfactants.
    Langmuir 2013, 29, 6519−6528.
    L. Ferrer-Tasies, E. Moreno, M. Cano-Sarabia, M. Aguilella-Arzo, A. Angelova, S. Lesieur, S. Ricart, J. Faraudo, N. Ventosa, J. Veciana.

  • Multifunctional Nanovesicle-Bioactive Conjugates Prepared by a One-Step Scalable Method Using CO2‑Expanded Solvents.
    Nano Lett. 2013, 13, 3766−3774.
    I. Cabrera, E. Elizondo, O. Esteban, J. L. Corchero, M. Melgarejo, D. Pulido, A. Córdoba, E. Moreno, U. Unzueta, E. Vazquez, I. Abasolo, S. Schwartz, Jr., A. Villaverde, F. Albericio, M. Royo, M. F. García-Parajo, N. Ventosa, J. Veciana.

2012

  • Supramolecular organization of protein-releasing functional amyloids solved in bacterial inclusion bodies.
    Acta Biomater. 2012, S1742-7061(12)00583-1.
    Cano-Garrido O, Rodríguez-Carmona E, Díez-Gil C, Vázquez E, Elizondo E, Cubarsi R, Seras-Franzoso J, Corchero JL, Rinas U, Ratera I, Ventosa N, Veciana J, Villaverde A, García-Fruitós E.

  • Crystallization of Microparticulate Pure Polymorphs of Active Pharmaceutical Ingredients Using CO2-Expanded Solvents.
    Cryst. Growth Des. 2012, 12, 1717−1726.
    S. Sala, A. Córdoba, E. Moreno-Calvo, E. Elizondo, M. Muntó, P. E. Rojas, M. À. Larrayoz, N. Ventosa, and J. Veciana.

  • Influence of the Preparation Route on the Supramolecular Organization of Lipids in a Vesicular System.
    J. Am. Chem.Soc. 2012, 134, 1918−1921.
    E. Elizondo, J. Larsen, Nikos S. Hatzakis, I. Cabrera, T. Bjørnholm, J. Veciana, D. Stamou, and N. Ventosa.

  • Cellular pharmacokinetics and intracellular activity against Listeria monocytogenes and Staphylococcus aureus of chemically modified and nanoencapsulated gentamicin.
    J Antimicrob Chemother. 2012, 67(9) 2158-2164.
    E. Imbuluzqueta, S. Lemaire, C. Gamazo, E. Elizondo, N. Ventosa, J. Veciana, F. Van Bambeke, M. J. Blanco-Prieto

  • Phase behavior of phytosterols and cholesterol in carbon dioxide-expanded ethanol.
    J. of Supercritical Fluids 2012, 63, 59– 68.
    F. Temelli, A. Córdoba, E. Elizondo, M. Cano-Sarabia, J. Veciana, N. Ventosa.

  • Nanostructuring molecular materials as particles and vesicles for drug delivery, using compressed and supercritical fluids.
    Nanomedicine 2012, 7(9), 1391–1408 (review).
    Elisa Elizondo, Jaume Veciana, Nora Ventosa.